发明名称 |
4-amino substituted-2-substituted-1,2,3,4-tetrahydroquinolines |
摘要 |
Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.
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申请公布号 |
US6140343(A) |
申请公布日期 |
2000.10.31 |
申请号 |
US19990391313 |
申请日期 |
1999.09.07 |
申请人 |
PFIZER |
发明人 |
DENINNO, MICHAEL P.;MAGNUS-ARYITEY, GEORGE T.;RUGGERI, ROGER B.;WESTER, RONALD T. |
分类号 |
C07D215/16;A61K;A61K31/47;A61K31/4706;A61K31/4709;A61K31/473;A61K45/00;A61P3/04;A61P3/06;A61P9/00;A61P9/10;A61P9/12;A61P31/00;C07D;C07D215/00;C07D215/42;C07D215/46;C07D221/06;C07D221/16;C07D413/12;C07D417/12;(IPC1-7):A61K31/47;C07D215/38 |
主分类号 |
C07D215/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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