Cell-targeting molecule comprising a mutant human carboxypeptidase A

摘要

PCT No. PCT/GB94/02483 Sec. 371 Date May 9, 1996 Sec. 102(e) Date May 9, 1996 PCT Filed Nov. 11, 1994 PCT Pub. No. WO95/13095 PCT Pub. Date May 18, 1995Conjugates of a cell targetting molecule and a mutant human carboxypeptidase A enzyme are provided. Suitable targetting molecules include antibodies, hormones, ligands, cytokines, antigens, oligonucleotides and peptidomimetics. Enzymes comprising a mutant human carboxypeptidase A enzyme are also provided.