发明名称 Use of phenylalkylamines for producing cholesterol lowering agents.
摘要 <p>Use of compounds of the formula <IMAGE> in which one of R<1> and R<2> is C1-7-alkyl and the other is C1-7-alkyl or C2-6-alkenylmethyl, L is C1-11-alkylene or C2-11-alkenylene which is optionally bonded via an O atom to the phenyl group, or L is 1,4-phenylene, n is 0 or, if L contains an O atom, n is 0 or 1, Q is C1-7-alkyl, C2-10-alkenyl or a group of the formula Q': <IMAGE> R is H, halogen, CF3, CN or NO2, R<3> and R<4> are H, C1-4-alkyl or halogen, and R<5> is H or, if R is H, H or halogen, and their pharmaceutically acceptable acid addition salts for producing cholesterol-lowering medicinal agents, and compounds covered by formula I.</p>
申请公布号 GR3033645(T3) 申请公布日期 2000.10.31
申请号 GR20000401332T 申请日期 2000.06.12
申请人 F. HOFFMANN-LA ROCHE AG 发明人 AEBI, JOHANNES;GUERRY, PHILIPE;JOLIDON, SYNESE, DR.;MORAND, OLIVIER
分类号 A61K31/24;A61K31/135;A61K31/137;A61K31/138;A61K31/277;A61P3/06;A61P9/10;C07C211/26;C07C217/18;C07C217/20;C07C217/22;C07C217/46;C07C225/08;C07C225/14;C07C225/16;C07C225/22;C07C255/56;(IPC1-7):A61K31/135 主分类号 A61K31/24
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