发明名称 |
Stable crystalline tetrahydrofolic acid salts |
摘要 |
<p>Crystalline calcium salt of (6R,S)-, (6R)- and (6S)-tetrahydrofolic acid. Also claimed is the magnesium salt. The crystallisation is preferably performed in a polar medium, preferably water or a mixture of water and an organic solvent most preferably acetic acid or a lower alcohol, at pH 7-10 at an elevated temperature and/or from a dilute solution</p> |
申请公布号 |
GR3033727(T3) |
申请公布日期 |
2000.10.31 |
申请号 |
GR20000401421T |
申请日期 |
2000.06.20 |
申请人 |
EPROVA AKTIENGESELLSCHAFT |
发明人 |
MUELLER, HANS RUDOLF;MOSER, RUDOLF;ULMANN, MARTIN;AMMANN, THOMAS |
分类号 |
A61K31/519;A61K31/522;A61P33/00;A61P35/00;A61P37/00;A61P39/02;C07D239/00;C07D241/00;C07D475/04;(IPC1-7):C07D475/04;A61K31/495 |
主分类号 |
A61K31/519 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|