Erythromycin a derivatives

摘要

PCT No. PCT/JP98/01240 Sec. 371 Date Sep. 21, 1999 Sec. 102(e) Date Sep. 21, 1999 PCT Filed Mar. 23, 1998 PCT Pub. No. WO98/42720 PCT Pub. Date Oct. 1, 1998An erythromycin A derivative represented by Formula (I): wherein R is a pyridyl group, a quinolyl group, a nitrophenyl group or a methoxyphenyl group, or a pharmaceutically acceptable salt thereof has a strong antibacterial activity not only against erythromycin-sensitive bacteria but also against certain erythromycin-resistant bacteria and Haemophilus influenzae.