发明名称 COMBINATION OF BISPHOSPHONATE AND TETRACYCLINE
摘要 Tissue-destructive conditions related to excess proteinase activity in a biological system are treated or prevented by administering to the system a composition which combines a tetracycline and a bisphosphonate in synergistic proteinase inhibiting amounts. The effectiveness of such compositions can be demonstrated in standard tests, for example by measuring tooth mobility.
申请公布号 WO0018230(A9) 申请公布日期 2000.10.26
申请号 WO1999US22199 申请日期 1999.09.24
申请人 THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK 发明人 RAMAMURTHY, NUNGAVARM, S.;GOLUB, LORNE, M.;SORSA, TIMO, A.;TERONEN, OLLI, P.;SALO, TUULA, A.
分类号 C12N9/64;A61K31/65;A61K31/66;A61K31/663;A61P1/02;A61P1/04;A61P9/00;A61P11/00;A61P11/06;A61P17/02;A61P17/06;A61P19/00;A61P19/02;A61P19/10;A61P27/02;A61P29/00;A61P31/18;A61P35/00;C12N9/99;(IPC1-7):A01N37/18;A01N57/00 主分类号 C12N9/64
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