| 摘要 |
<p>Sulfonamide derivatives having a matrix metalloprotease inhibiting effect, which are compounds represented by general formula (I), optical isomers of the same, pharmaceutically acceptable salts of both, or solvates of them: wherein R?1 and R2¿ are each independently hydrogen, optionally substituted lower alkyl, or the like; R3 is optionally substituted aryl, optionally substituted heteroaryl, or the like; X is -CH=CH-, -O-, or -S-; and Y is NHOH, hydroxyl, or lower alkyloxy.</p> |
