摘要 |
<p>The present invention concerns a process for the preparation of a compound of formula (1) or salts thereof, comprising the reaction of a compound of formula (2) in the presence of an oxidant and a chiral osmium complex, wherein the hydroxy groups attached to the carbon atoms 3 and 4 of the piperidine cycle of formula (1) are in cis position and A, R?1 and R2¿ are as defined in the description and claims.</p> |