A METHOD OF REVERSING THYMIC ATROPHY BY ADMINISTERING AN ANTAGONIST OF AN OVERPRODUCED CYTOKINE

摘要

The present invention relates, in general, to cytokines and, in particular, to a method of reconstituting the T cell arm of a mammalian immune system in those diseases or conditions in which the T cell pool is damaged. More specifically, the present invention relates to a method of reversing thymic atrophy associated aging and to a method of treating T cell lymphopenia. The methods comprise administering cytokines, agonists thereof, that are underproduced in these physiological states and/or administering antagonists of cytokines that are overproduced.