发明名称 |
DIBENZOAZULENE DERIVATIVES FOR THE TREATMENT OF THROMBOSIS, OSTEOPOROSIS, ARTERIOSCLEROSIS |
摘要 |
The invention relates to compounds of formula (I) wherein R1, R2, R3, m and n are defined as in claim 1 and to their physiologically acceptable salts and solvates. The inventive substances are used as integrin-inhibiting substance s especially in the prophylaxis and treatment of cardiovascular disorders, of thrombosis, cardiac infarction, coronary heart diseases, arteriosclerosis, osteoporosis, in pathological conditions that are caused or propagated by th e angiogenesis, and in tumor therapy.
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申请公布号 |
CA2367359(A1) |
申请公布日期 |
2000.10.26 |
申请号 |
CA20002367359 |
申请日期 |
2000.04.01 |
申请人 |
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG |
发明人 |
GOODMAN, SIMON;GOTTSCHLICH, RUDOLF;STAHLE, WOLFGANG |
分类号 |
C07D239/14;A61K31/4402;A61K31/505;A61P3/10;A61P7/02;A61P9/00;A61P9/10;A61P13/12;A61P17/06;A61P19/00;A61P19/02;A61P19/10;A61P27/02;A61P27/06;A61P29/00;A61P31/04;A61P31/10;A61P31/12;A61P35/00;A61P43/00;C07C69/00;C07D213/74;(IPC1-7):C07D213/74;A61K31/440 |
主分类号 |
C07D239/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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