METHODS OF TREATMENT OF TYPE 2 DIABETES,申请号WO1999US24890-传众专利搜索

发明名称	METHODS OF TREATMENT OF TYPE 2 DIABETES
摘要	<p>The present invention relates generally to the field of diabetes. More particularly, it concerns the identification of genes responsible for NIDDM1 for use in diagnostic and therapeutic applications. The present invention demonstrates that the NIDDM1 locus is, in fact, the calpain 10 gene. The invention further relates to the discovery that analysis of mutations in calpain genes and gene products can be diagnostic for type 2 diabetes. The invention also contemplates methods of treating diabetes in view of the fact that calpain mutations can cause diabetes. Further, the invention relates to novel polynucleotides of the NIDDM1 locus and polypeptides encoded by such polynucleotides.</p>
申请公布号	WO0023603(A8)	申请公布日期	2000.10.26
申请号	WO1999US24890	申请日期	1999.10.21
申请人	ARCH DEVELOPMENT CORPORATION;BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;POLONSKY, KENNETH, S.;HORIKAWA, YUKIO;ODA, NAOHISA;SREENAN, SEAMUS;ZHOU, YUN-PING;OTANI, KENICHI;HANIS, CRAIG, L.;BELL, GRAEME, I.;COX, NANCY, J.	发明人	POLONSKY, KENNETH, S.;HORIKAWA, YUKIO;ODA, NAOHISA;SREENAN, SEAMUS;ZHOU, YUN-PING;OTANI, KENICHI;HANIS, CRAIG, L.;BELL, GRAEME, I.;COX, NANCY, J.
分类号	A61P3/10;C12N9/64;C12N15/12;C12Q1/68;(IPC1-7):C12N15/63;A61K38/55	主分类号	A61P3/10
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