| 摘要 |
Sulfonamide derivatives having a matrix metalloprotease inhibiting effect, which are compounds represented by general formula (I), optical isomers of t he same, pharmaceutically acceptable salts of both, or solvates of them: wherei n R1 and R2 are each independently hydrogen, optionally substituted lower alky l, or the like; R3 is optionally substituted aryl, optionally substituted heteroaryl, or the like; X is -CH=CH-, -O-, or -S-; and Y is NHOH, hydroxyl, or lower alkyloxy.
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