摘要 |
The present invention relates to a family of neuronal nicotinic acetylcholine receptors comprised of neuronal agonist and non-agonist binding subunits, and DNA sequences encoding such subunits. These novel neuronal nicotinic acetylcholine receptor subunits include the agonist binding subunits alpha2, alpha3, alpha4, and alpha5, plus non-agonist binding subunits beta2, beta3 and beta4. Representative cDNA clones that contain the DNA sequences of the invention have been deposited with the American Type Culture Collection for patent purposes.
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申请人 |
THE SALK INSTITUTE FOR BIOLOGICAL STUDIES |
发明人 |
HEINEMANN, STEPHEN FOX;PATRICK, JAMES WARNER;BOULTER, JAMES RICHARD;DENERIS, EVAN SAMUEL;WADA, KEIJI;BALLIVET, MARC CHARLES;GOLDMAN, DANIEL JAY;CONNOLLY, JOHN GERARD;DUVOISIN, ROBERT MICHAEL;HEINEMANN, EDEN DEER |