Multiple sclerosis virus

摘要

PCT No. PCT/GB94/01129 Sec. 371 Date Mar. 18, 1996 Sec. 102(e) Date Mar. 18, 1996 PCT Filed May 24, 1994 PCT Pub. No. WO94/28138 PCT Pub. Date Dec. 8, 1994The present invention provides a polynucleotide in substantially isolated form comprising a sequence of nucleotides which is capable of selectively hybridizing to the genome of the human multiple sclerosis virus (HMSV) or the complement thereof, wherein HMSV is characterized by: (i) a positive stranded RNA genome; (ii) said genome comprising one or more open reading frames (ORF) encoding protein(s) or polyprotein(s); (iii) said genome encoding a reverse transcriptase enzyme; and (v) said genome comprising nucleotide sequences which are homologous to or selectively hybridizable with any one of the nucleotide sequences illustrated in SEQ ID NOS:1 to 6.