| 发明名称 |
Oligonucleotides specific for the marORAB operon |
| 摘要 |
Disclosed are synthetic oligonucleotides complementary to a transcript of the marORAB operon which inhibit expression of a gene in the operon. Also disclosed are methods of reducing bacterial resistance to antibiotics, and pharmaceutical formulations containing marORAB-specific oligonucleotides of the invention.
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| 申请公布号 |
US6136602(A) |
申请公布日期 |
2000.10.24 |
| 申请号 |
US19980027130 |
申请日期 |
1998.02.20 |
| 申请人 |
HYBRIDON, INC.;TRUSTEES OF TUFTS COLLEGE |
发明人 |
LEVY, STUART B.;VON HOFE, ERIC |
| 分类号 |
C12N15/09;A61K31/18;A61K31/433;A61K31/4409;A61K31/445;A61K31/47;A61K31/496;A61K31/505;A61K31/545;A61K31/65;A61K31/7008;A61K31/7048;A61K31/708;A61K38/00;A61K45/00;A61K48/00;A61P31/04;C12N15/113;C12Q1/68;(IPC1-7):C07H21/04 |
主分类号 |
C12N15/09 |
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