发明名称 |
Covalent attachment of unmodified nucleic acids to silanized solid phase surfaces |
摘要 |
This invention relates to a composition having a nucleic acid molecule covalently coupled to a solid support by means of a covalent linkage. The nucleic acid molecule is covalently coupled to the solid support by a silane. The composition can be used in nucleic acid hybridization assays and sequencing by hybridization assays.
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申请公布号 |
US6136962(A) |
申请公布日期 |
2000.10.24 |
申请号 |
US19980102371 |
申请日期 |
1998.06.23 |
申请人 |
ORCHID BIOSCIENCES, INC. |
发明人 |
SHI, JUFANG;BOYCE-JACINO, MICHAEL T. |
分类号 |
G01N33/53;C12M1/00;C12N15/09;C12Q1/68;G01N33/566;G01N37/00;(IPC1-7):C07H21/04 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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