发明名称 |
Antibacterial and antifungal flavanones from Eysenhardtia texana |
摘要 |
An activity-guided fractionation of a methanol-dichloromethane extract obtained from the aerial parts of Eysenhardtia texana Kunth. (Fabaceae) led to the isolation of two new antibacterial and antifungal flavanones. Their structures were established as 4',5,7-trihydroxy-8-methyl-6-(3-methyl-[2-butenyl])-(2S)-flavanone and 4',5,7-trihydroxy-6-methyl-8-(3-methyl-[2-butenyl])-(2S)-flavanone on the basis of their UV, ID and 2D-NMR spectra. These compounds have potent antibacterial and antifungal activity as measured by bioassay.
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申请公布号 |
US6136849(A) |
申请公布日期 |
2000.10.24 |
申请号 |
US19990413065 |
申请日期 |
1999.10.06 |
申请人 |
HOFFMANN, JOSEPH J.;WAECHTER, GERALD A.;GUTTERMAN, JORDAN U. |
发明人 |
HOFFMANN, JOSEPH J.;WAECHTER, GERALD A.;GUTTERMAN, JORDAN U. |
分类号 |
C07D311/32;(IPC1-7):A61K31/35 |
主分类号 |
C07D311/32 |
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