发明名称 Cyclic amine modulations of chemokine receptor activity
摘要 The present invention is directed to cyclic amines of the formula I: (wherein R1, R2, R3, m and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-1, CCR-2, CCR-2A, CCR-2B, CCR-3, CCR-4, CCR-5, CXCR-3, and/or CXCR-4.
申请公布号 US6136827(A) 申请公布日期 2000.10.24
申请号 US19980120010 申请日期 1998.07.21
申请人 MERCK & CO., INC. 发明人 CALDWELL, CHARLES G.;FINKE, PAUL E.;MACCOSS, MALCOLM;MEURER, LAURA C.;MILLS, SANDER G.;OATES, BRYAN
分类号 A61K31/445;C07D211/56;(IPC1-7):A61K31/445 主分类号 A61K31/445
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