发明名称 Pyrrolidine modulators of chemokine receptor activity
摘要 The present invention is directed to pyrrolidine compounds of the formula I:(wherein R1, R2, R3, R4, R5, R6, R14 and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.
申请公布号 AU4197900(A) 申请公布日期 2000.10.23
申请号 AU20000041979 申请日期 2000.04.05
申请人 MERCK & CO., INC. 发明人 KEVIN CHAPMAN;JEFFREY HALE;DOOSEOP KIM;CHRISTOPHER LYNCH;SHRENIK SHAH;KOTHANDARAMAN SHANKARAN;DONG-MING SHEN;CHRISTOPHER WILLOUGHBY;MALCOLM MACCOSS;SANDER G. MILLS;JENNIFER L. LOEBACH;RAVINDRA N GUTHIKONDA
分类号 A61K31/454;A61K31/4545;A61K31/4985;A61K31/506;A61K31/517;A61K31/519;A61K31/551;A61K31/553;A61P9/10;A61P11/02;A61P11/06;A61P17/00;A61P27/14;A61P29/00;A61P31/18;A61P37/00;A61P37/06;A61P37/08;A61P43/00;C07D207/09;C07D401/06;C07D401/14;C07D403/12;C07D409/14;C07D413/14;C07D417/14;C07D471/04;C07D487/04;C07D495/04;C07D513/04 主分类号 A61K31/454
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