| 发明名称 |
Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds |
| 摘要 |
The present invention relates to cinnamide compounds of formula (I), in which at least one of R1 to R5 is a "cis-cinnamide" (a) or a "trans-cinnamide" (b) and the other variables are as defined in the claims, that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions containing these compounds and to methods of inhibiting inflammation or suppressing immune response in a mammal. <CHEM> |
| 申请公布号 |
AU4194400(A) |
申请公布日期 |
2000.10.23 |
| 申请号 |
AU20000041944 |
申请日期 |
2000.04.03 |
| 申请人 |
ABBOTT LABORATORIES |
发明人 |
JAMES LINK;GANG LIU;ZHONGHUA PEI;THOMAS W. VON GELDERN;MARTIN WINN;ZHILI XIN;SHELDON WANG;STEVEN A. BOYD;GUI-DONG ZHU;JENNIFER C. FREEMAN;INDRANI W. GUNAWARDANA;MICHAEL A. STAEGER;HWAN-SOO JAE;JOHN K. LYNCH |
| 分类号 |
C07D243/08;A61K;A61K31/10;A61K31/165;A61K31/33;A61K31/40;A61K31/4015;A61K31/41;A61K31/417;A61K31/438;A61K31/44;A61K31/4427;A61K31/445;A61K31/4468;A61K31/451;A61K31/453;A61K31/454;A61K31/4545;A61K31/472;A61K31/496;A61K31/4965;A61K31/506;A61K31/5375;A61K31/5377;A61K31/54;A61K31/541;A61K31/55;A61K31/551;A61P;A61P29/00;A61P37/06;C07C;C07C323/60;C07C323/62;C07D;C07D205/04;C07D207/09;C07D207/12;C07D207/14;C07D207/16;C07D207/26;C07D207/27;C07D207/273;C07D209/08;C07D209/12;C07D211/20;C07D211/22;C07D211/46;C07D211/60;C07D211/62;C07D211/64;C07D211/66;C07D211/70;C07D213/40;C07D213/74;C07D213/81;C07D215/24;C07D217/02;C07D217/04;C07D217/06;C07D233/61;C07D239/42;C07D241/04;C07D241/24;C07D257/04;C07D279/12;C07D295/18;C07D295/185;C07D295/20;C07D295/205;C07D295/22;C07D295/26;C07D307/24;C07D307/52;C07D307/68;C07D317/58;C07D317/66;C07D319/18;C07D401/04;C07D401/12;C07D405/12;C07D417/12;C07D471/20;C07D487/04;C07D491/113;C07D521/00 |
主分类号 |
C07D243/08 |
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