发明名称 ANTICONVULSANT DERIVATIVES USEFUL IN LOWERING BLOOD PRESSURE
摘要 Use of anticonvulsant derivatives of formula (I) for lowering blood pressure particularly in overweight individuals, wherein X is CH2 or oxygen; R1 is hydrogen or alkyl; and R2, R3, R4 and R5 are independently hydrogen or alkyl and, when X is CH2, R4 and R5 may be alkene groups joined to form a benzene ring and, when X is oxygen, R2 and R3, and/or R4 and R5 together may be a methylenedioxy group of formula (II), wherein R6 and R7 are the same or different and are hydrogen, or alkyl and are joined to form a cyclopentyl or cyclohexyl ring.
申请公布号 WO0061136(A1) 申请公布日期 2000.10.19
申请号 WO2000US08337 申请日期 2000.03.30
申请人 ORTHO-MCNEIL PHARMACEUTICAL, INC. 发明人 COTTRELL, SANDRA, C.
分类号 C07H9/04;A61K31/255;A61K31/35;A61K31/351;A61K31/7048;A61P9/12;(IPC1-7):A61K31/255;A61K31/704 主分类号 C07H9/04
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