发明名称 |
3-BICYCLOARYL-2-AMINOMETHYL BICYCLOALKANES AS SEROTONINE REUPTAKE INHIBITORS |
摘要 |
A pharmaceutical compound of formula (I) in which R<1> and R<2> are each hydrogen or C1-4 alkyl, or R<1> and R<2> together with the nitrogen atom to which they are attached form an azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl or morpholino group, said group being optionally substituted with 1 to 3 C1-4 alkyl substituents, R<3> is a naphthyl, indolyl, benzothienyl, benzofuranyl, benzothiazolyl, quinolinyl or isoquinolinyl group, said group being optionally substituted, and n is 1 or 2; or a salt or ester thereof.
|
申请公布号 |
WO0061539(A1) |
申请公布日期 |
2000.10.19 |
申请号 |
WO2000GB01294 |
申请日期 |
2000.04.06 |
申请人 |
ELI LILLY AND COMPANY LIMITED;KEENAN, MARTINE;MILUTINOVIC, SANDRA, GINETTE;TUPPER, DAVID, EDWARD |
发明人 |
KEENAN, MARTINE;MILUTINOVIC, SANDRA, GINETTE;TUPPER, DAVID, EDWARD |
分类号 |
C07D333/54;A61K31/13;A61K31/16;A61K31/381;A61K31/4025;A61K31/404;A61P1/04;A61P1/08;A61P3/04;A61P9/04;A61P9/12;A61P15/10;A61P25/00;A61P25/04;A61P25/06;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/32;A61P25/34;A61P25/36;C07C211/30;C07C215/64;C07C217/74;C07C233/58;C07D209/08;C07D209/14;C07D209/18;C07D333/58;C07D333/60;C07D333/62;(IPC1-7):C07C211/30;A61K31/137 |
主分类号 |
C07D333/54 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|