| 发明名称 |
USE OF ANTI-VEGF ANTIBODY TO ENHANCE RADIATION IN CANCER THERAPY |
| 摘要 |
We have discovered that VEGF expression is induced following exposure tumors to ionizing radiation (IR) both in vitro and in vivo. We found that treatment of tumor-bearing mice with a neutralizing antibody to VEGF prior to irradiation is associated with greater than additive antitumor effects.
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| 申请公布号 |
WO0061186(A1) |
申请公布日期 |
2000.10.19 |
| 申请号 |
WO2000US09255 |
申请日期 |
2000.04.07 |
| 申请人 |
WEICHSELBAUM, RALPH, R. |
发明人 |
WEICHSELBAUM, RALPH, R.;KUFE, DONALD, W. |
| 分类号 |
C07K16/22;(IPC1-7):A61K39/395;C07K16/00 |
主分类号 |
C07K16/22 |
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