REFLECTIVELY COATED OPTICAL WAVEGUIDE AND FLUIDICS CELL INTEGRATION

摘要

A multimode waveguide device for assays includes a multimode waveguide (12) with a patterned, reflective surface coating (22). The exposed portion of the reflectively coated waveguide surface are for analyte recognition. A fluidics cell (10) is attached to the waveguide so that the channel or channels (30) of the fluidics cell (10) match with the exposed portion or portions of the waveguide surface. The channel or channels (30) direct one or more sample fluids over the exposed portion or portions of the waveguide surface. The reflective coating minimizes loss and scattering of excitation and fluorescence light during a fluorescence assay.