发明名称 |
USE OF mCRP TO ENHANCE IMMUNE RESPONSES |
摘要 |
The invention provides a method of enhancing an immune response to an immunogen in an animal. The method comprises administering to the animal an effective amount of the immunogen and an effective amount of a modified C-reactive protein (mCRP) or a mutant-mCRP. The invention also provides a vaccine and a method of producing this vaccine. The vaccine comprises an immunogen and an mCRP or a mutant-mCRP in a pharmaceutically-acceptable vehicle. The invention further provides a kit for immunizing an animal to an immunogen comprising (1) a container holding the immunogen and a container holding an mCRP or a mutant-mCRP or (2) a container holding the immunogen and an mCRP or a mutant-mCRP. The invention also provides a method of elicing an immune response to a hapten in an animal. The method comprises administering to the animal an effective amount of the hapten in association with an effective amount of an mCRP or a mutant-mCRP. The invention furhter provides a vaccine and a method of producing this vaccine. The vaccine comprises a hapten and an mCRP or a mutant-mCRP in a pharmaceutically-acceptable vehicle. Finally, the invention provides a kit for immunizing an animal to a hapten comprising a container holding the hapten and an mCRP or a mutant-mCRP.
|
申请公布号 |
WO0061181(A1) |
申请公布日期 |
2000.10.19 |
申请号 |
WO1999US18886 |
申请日期 |
1999.08.19 |
申请人 |
IMMTECH INTERNATIONAL, INC. |
发明人 |
POTEMPA, LAWRENCE, A.;RADOSEVICH, JAMES, A. |
分类号 |
A61K35/00;A61K39/08;A61K39/39;A61P37/04;(IPC1-7):A61K39/00;A61K39/385 |
主分类号 |
A61K35/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|