| 发明名称 |
CASPASE INHIBITORS AND THE USE THEREOF |
| 摘要 |
The present invention is directed to novel dipeptide thereof, represented by general formula (I); where R1-R3 X and Y are defined herein. The present invention also relates to the discovery that Compounds having Formula (I) are potent inhibitors of caspases and apoptotic cell death. Therefore, the inhibitors of this invention can retard or block cell death in a variety of clinical conditions in which the loss of cells, tissues of entire organs occurs.
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| 申请公布号 |
CA2369619(A1) |
申请公布日期 |
2000.10.19 |
| 申请号 |
CA20002369619 |
申请日期 |
2000.04.07 |
| 申请人 |
CYTOVIA, INC. |
发明人 |
CAI, SUI XIONG;WANG, YAN;MILLS, GORDON B.;WEBER, ECKARD;GREEN, DOUGLAS R. |
| 分类号 |
C12N9/99;A61K38/00;A61P1/02;A61P1/04;A61P1/08;A61P1/16;A61P1/18;A61P3/10;A61P7/00;A61P7/06;A61P7/08;A61P9/04;A61P9/10;A61P13/10;A61P13/12;A61P15/08;A61P17/02;A61P17/06;A61P17/14;A61P25/00;A61P25/02;A61P25/14;A61P25/16;A61P25/28;A61P25/32;A61P27/02;A61P27/06;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P35/00;A61P37/00;A61P37/02;A61P39/02;A61P43/00;C07C237/22;C07C271/22;C07C311/19;C07D295/205;C07D311/16;C07D311/66;C07K5/06;C12N1/16;(IPC1-7):C07C229/00;C07C205/00;C07C61/08 |
主分类号 |
C12N9/99 |
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