摘要 |
An L-amino acid is produced by culturing, in a medium containing methanol as the main carbon source, a bacterium belonging to the genus Methylophilus, being capable of growing with the use of methanol as the main carbon source, and having an L-amino acid productivity (for example, a bacterium belonging to the genus Methylophilus having been transformed by introducing a DNA encoding dihydrodipicolinate synthase free from the feedback inhibition by L-lysine and another DNA encoding aspartokinase free from the feedback inhibition by L-lysine into the cell and thus having enhanced dihydrodipicolinate synthase activity and aspartokinase activity), or a bacterium belonging to the genus Methylophilus and having a casamino acid requirement. |
申请人 |
AJINOMOTO CO., INC.;GUNJI, YOSHIYA;YASUEDA, HISASHI;SUGIMOTO, SHINICHI;TSUJIMOTO, NOBUHARU;SHIMAOKA, MEGUMI;MIYATA, YURI;OBA, MANAMI |
发明人 |
GUNJI, YOSHIYA;YASUEDA, HISASHI;SUGIMOTO, SHINICHI;TSUJIMOTO, NOBUHARU;SHIMAOKA, MEGUMI;MIYATA, YURI;OBA, MANAMI |