| 发明名称 |
Antisense modulation of PI3 kinase p110 beta expression |
| 摘要 |
Antisense compounds, compositions and methods are provided for modulating the expression of PI3 kinase p110 beta. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PI3 kinase p110 beta. Methods of using these compounds for modulation of PI3 kinase p110 beta expression and for treatment of diseases associated with expression of PI3 kinase p110 beta are provided.
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| 申请公布号 |
US6133032(A) |
申请公布日期 |
2000.10.17 |
| 申请号 |
US19990392350 |
申请日期 |
1999.09.09 |
| 申请人 |
ISIS PHARMACEUTICAL INC. |
发明人 |
MONIA, BRETT P.;COWSERT, LEX M. |
| 分类号 |
C12N15/09;A61K9/10;A61K9/107;A61K31/7115;A61K31/712;A61K31/7125;A61K38/00;A61K48/00;A61P19/02;A61P29/00;A61P35/00;A61P43/00;C07H21/00;C07H21/04;C12N15/113;(IPC1-7):C07H21/04;C12N15/00;C12Q1/68 |
主分类号 |
C12N15/09 |
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