| 发明名称 |
Hedgehog-derived polypeptides |
| 摘要 |
The present invention provides two novel polypeptides, referred to as the "N" and "C" fragments of hedgehog, or N-terminal and C-terminal fragments, respectively, which are derived after specific cleavage at a G &darr& CF site recognized by the autoproteolytic domain in the native protein. Also provided are methods of use of the N and C fragments.
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| 申请公布号 |
US6132728(A) |
申请公布日期 |
2000.10.17 |
| 申请号 |
US19950567357 |
申请日期 |
1995.12.04 |
| 申请人 |
THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE;UNIVERSITY OF WASHINGTON |
发明人 |
BEACHY, PHILIP A.;MOON, RANDALL T.;PORTER, JEFFREY A. |
| 分类号 |
C12N15/09;A61K38/00;A61P25/00;C07K14/435;C07K16/18;C12N5/10;C12N15/62;C12P21/04;C12P21/08;G01N33/50;G01N33/92;(IPC1-7):A61K38/18;C07K14/475 |
主分类号 |
C12N15/09 |
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