发明名称 Preparation of dtpa esters with different ester groups
摘要 The synthesis of compounds of formula (XI) wherein each R4 is a removable protecting group; R5 is a removable protecting group different from and removable separately from R4; each R6 and R8 is a linking moiety having 1 to 10 carbon atoms; and R9 is hydrogen or a C1 to C50 alkyl moiety, is disclosed. These compounds are useful intermediates in the synthesis of compounds of formula (X). These compounds are useful in the preparation of nuclear pharmaceuticals such as those used for tumor imaging or tumor therapy.
申请公布号 AU4019000(A) 申请公布日期 2000.10.16
申请号 AU20000040190 申请日期 2000.03.21
申请人 MALLINCKRODT, INC. 发明人 SAMUEL I. ACHILEFU;ANANTHACHARI SRINIVASAN
分类号 C07C227/14;C07C229/16 主分类号 C07C227/14
代理机构 代理人
主权项
地址