发明名称 |
Use of a lectin or conjugates for modulation of c-fibre activity |
摘要 |
The present invention relates to the treatment of pain and to compounds that modulate C-fibre activity. In particular, the present invention relates to the use of a lectin in the manufacture of a medicament for modulation of C-fibre neuron activity, and to lectin conjugates. The lectin conjugates comprise a lectin coupled to a peptide or protein, wherein the peptide or protein is substantially free of Clostridial neurotoxin enzyme activity. The present invention also concerns methods for manufacturing conjugates. The compounds and compositions described have particular application in the treatment of diseases of which C-fibre activity is a component. Such diseases include pain, inflamation, psoriasis and other C-fibre related conditions. |
申请公布号 |
AU3569000(A) |
申请公布日期 |
2000.10.16 |
申请号 |
AU20000035690 |
申请日期 |
2000.03.31 |
申请人 |
MICROBIOLOGICAL RESEARCH AUTHORITY |
发明人 |
KEITH ALAN FOSTER;JOHN ANDREW CHADDOCK;CONRAD PADRAIG QUINN |
分类号 |
C12N15/09;A61K38/00;A61K38/16;A61K47/48;A61K48/00;A61P1/06;A61P11/02;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P25/00;A61P25/04;A61P25/06;A61P29/00;A61P43/00;C07K14/42;C07K19/00;C12N15/29;C12P21/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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