| 摘要 |
Sulfonamide derivatives having matrix metalloprotease inhibiting effects, which are compounds represented by general formula (I), optical isomers of the same, pharmaceutically acceptable salts of both, or hydrates thereof wherein R<1> is hydrogen, optionally substituted lower alkyl, or the like; R<2> is a single bond, optionally substituted arylene, or the like; R<3> is a single bond, -CC-, or the like; R<4> is optionally substituted aryl or the like; M is hydroxyl or the like; and m is 0 or 1. |
