发明名称 |
Compositions and methods for effecting the levels of high density lipoprotein (hdl) cholesterol and apolipoprotein ai, very low density lipoprotein (vldl) cholesterol and low density lipoprotein (ldl) cholesterol |
摘要 |
Compositions and methods for raising the level of HDL cholesterol and apolipoprotein AI in a patient and for lowering the levels of VLDL cholesterol and LDL cholesterol in a patient, including compositions and methods which effect the expression of a gene, LIPG, which encodes a lipase enzyme that is a member of the tryacylglycerol lipase family or which effect the enzymatic activity of the enzyme. |
申请公布号 |
AU3918700(A) |
申请公布日期 |
2000.10.16 |
申请号 |
AU20000039187 |
申请日期 |
2000.03.24 |
申请人 |
AVENTIS PHARMACEUTICALS PRODUCTS INC.;THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
MICHAEL JAYE;KEVIN J. LYNCH;DILIP V AMIN;KIM-ANH THI DOAN;DAWN MARCHADIER;CYRILLE MAUGEAIS;DANIEL J. RADER;JOHN A. KRAWIEC;VICTORIA J. SOUTH |
分类号 |
G01N33/50;A61K31/7088;A61K35/76;A61K38/00;A61K38/55;A61K39/395;A61K45/00;A61K48/00;A61P3/06;A61P43/00;C07K16/40;C12N9/20;C12N15/09;G01N33/15;G01N33/53;G01N33/566 |
主分类号 |
G01N33/50 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|