发明名称 Compositions and methods for effecting the levels of high density lipoprotein (hdl) cholesterol and apolipoprotein ai, very low density lipoprotein (vldl) cholesterol and low density lipoprotein (ldl) cholesterol
摘要 Compositions and methods for raising the level of HDL cholesterol and apolipoprotein AI in a patient and for lowering the levels of VLDL cholesterol and LDL cholesterol in a patient, including compositions and methods which effect the expression of a gene, LIPG, which encodes a lipase enzyme that is a member of the tryacylglycerol lipase family or which effect the enzymatic activity of the enzyme.
申请公布号 AU3918700(A) 申请公布日期 2000.10.16
申请号 AU20000039187 申请日期 2000.03.24
申请人 AVENTIS PHARMACEUTICALS PRODUCTS INC.;THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 发明人 MICHAEL JAYE;KEVIN J. LYNCH;DILIP V AMIN;KIM-ANH THI DOAN;DAWN MARCHADIER;CYRILLE MAUGEAIS;DANIEL J. RADER;JOHN A. KRAWIEC;VICTORIA J. SOUTH
分类号 G01N33/50;A61K31/7088;A61K35/76;A61K38/00;A61K38/55;A61K39/395;A61K45/00;A61K48/00;A61P3/06;A61P43/00;C07K16/40;C12N9/20;C12N15/09;G01N33/15;G01N33/53;G01N33/566 主分类号 G01N33/50
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