摘要 |
The present invention is directed to pyrrolidine compounds of the formula (I) (wherein R<1>, R<2>, R<3>, R<4>, R<5>, R<6> and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.
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申请人 |
MERCK & CO., INC.;CALDWELL, CHARLES;CHAPMAN, KEVIN;HALE, JEFFREY;KIM, DOOSEOP;LYNCH, CHRISTOPHER;MACCOSS, MALCOLM;MILLS, SANDER, G.;WILLOUGHBY, CHRISTOPHER;BERK, SCOTT;KIM, RONALD, M. |
发明人 |
CALDWELL, CHARLES;CHAPMAN, KEVIN;HALE, JEFFREY;KIM, DOOSEOP;LYNCH, CHRISTOPHER;MACCOSS, MALCOLM;MILLS, SANDER, G.;WILLOUGHBY, CHRISTOPHER;BERK, SCOTT;KIM, RONALD, M. |