发明名称 PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
摘要 The present invention is directed to pyrrolidine compounds of the formula (I) (wherein R<1>, R<2>, R<3>, R<4>, R<5>, R<6> and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.
申请公布号 WO0059498(A1) 申请公布日期 2000.10.12
申请号 WO2000US09074 申请日期 2000.04.05
申请人 MERCK & CO., INC.;CALDWELL, CHARLES;CHAPMAN, KEVIN;HALE, JEFFREY;KIM, DOOSEOP;LYNCH, CHRISTOPHER;MACCOSS, MALCOLM;MILLS, SANDER, G.;WILLOUGHBY, CHRISTOPHER;BERK, SCOTT;KIM, RONALD, M. 发明人 CALDWELL, CHARLES;CHAPMAN, KEVIN;HALE, JEFFREY;KIM, DOOSEOP;LYNCH, CHRISTOPHER;MACCOSS, MALCOLM;MILLS, SANDER, G.;WILLOUGHBY, CHRISTOPHER;BERK, SCOTT;KIM, RONALD, M.
分类号 A61P9/10;A61P31/18;A61P37/06;A61P37/08;C07D401/06;C07D401/14;C07D409/14;C07D413/14;C07D417/14;C07D491/10;C07F9/59;C07F9/6558;(IPC1-7):A61K31/165;A61K31/215;A61K31/24;A61K31/40;A61K31/402;A61K31/415;A61K31/417;A61K31/419;A61K31/422;A61K31/424;A61K31/427;A61K31/433;A61K31/435;A61K31/44;A61K31/442;A61K31/443;A61K31/444;A61K31/445;A61K31/454;A61K31/47;A61K31/470;A61K31/472;A61K31/495;A61K31/496;A61K31/50;A61K31/501;A61K31/535;C07C233/59;C07C233/60;C07C233/61;C07C233/63;C07C233/64;C07C233/66;C07C233/68;C07C233/70;C07C233/77;C07C235/02;C07C235/26;C07C235/30;C07C235/32;C07C235/36;C07C235/38;C07C235/42;C07C235/70;C07D207/04;C07D207/12;C07D207/14;C07D207/16;C07D211/04;C07D211/06;C07D211/14;C07D211/18;C07D211/22;C07D211/24;C07D211/26;C07D211/34;C07D211/38;C07D211/40;C07D211/44;C07D211/60;C07D211/62;C07D211/68;C07D211/70;C07D211/72;C07D211/74;C07D213/04;C07D213/06;C07D213/24;C07D213/28;C07D213/30;C07D213/36;C07D213/44;C07D213/46;C07D213/55;C07D213/56;C07D215/02;C07D215/04;C07D239/24;C07D239/26;C07D241/04;C07D241/10;C07D241/12;C07D241/36;C07D241/38;C07D241/40;C07D243/02;C07D243/08;C07D295/04;C07D401/04;C07D403/06;C07D403/14;C07D411/14;C07D471/10;C07D471/12;C07D471/14;C07D487/02;C07D487/04;C07F9/02 主分类号 A61P9/10
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