发明名称 LOW DOSE ESTROGEN INTERRUPTED HORMONE REPLACEMENT THERAPY
摘要 A hormone replacement therapy, comprising a plurality of daily doses of a pharmaceutical preparation, the doses being administered continuously and consecutively in alternating phases of three daily doses, a relatively dominant estrogenic activity phase comprising three daily doses of a substance exhibiting estrogenic activity equivalent to about 1 mg per day of 17 beta -estradiol per day, and a relatively dominant progestagenic activity phase of a combination of a substance exhibiting estrogenic activity equivalent to about 1 mg per day of 17 beta -estradiol and a substance exhibiting progestogenic activity equivalent to about 90 mu g per day of norgestimate.
申请公布号 WO0059577(A1) 申请公布日期 2000.10.12
申请号 WO2000CA00315 申请日期 2000.03.22
申请人 JENCAP RESEARCH LTD.;ORTHO-MCNEIL PHARMACEUTICAL INC. 发明人 CASPER, ROBERT, F.;SHANGOLD, GARY, A.;AUSMANAS, MILITZA, K.
分类号 A61K9/20;A61K31/565;A61K31/566;A61K31/567;A61K31/57;A61K31/575;A61P5/24;A61P5/30;A61P15/12;A61P43/00;(IPC1-7):A61P5/24 主分类号 A61K9/20
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