发明名称 WATER-SOLUBLE TRIOXANES AS POTENT AND SAFE ANTIMALARIAL AGENTS
摘要 Biologically-active, water soluble, 3-substituted trioxanes of formula (I) wherein R represents a substituted aryl group, a substituted or unsubstituted heteroaryl group or an alkyl group, and C12-(p-carboxy)benzyloxy trioxanes of formula (II) wherein R represents a substituted or unsubstituted alkyl, alkenyl, aryl or heteroaryl group and methods for their use as antiparasitic agents, particularly for the treatment of malaria.
申请公布号 WO0059501(A1) 申请公布日期 2000.10.12
申请号 WO2000US09309 申请日期 2000.04.07
申请人 JOHNS HOPKINS UNIVERSITY;POSNER, GARY, H.;PARKER, MICHAEL, H.;KRASAVIN, MIKHAIL;SHAPIRO, THERESA, A. 发明人 POSNER, GARY, H.;PARKER, MICHAEL, H.;KRASAVIN, MIKHAIL;SHAPIRO, THERESA, A.
分类号 A61K31/335;A61P33/06;C07D493/10;(IPC1-7):A61K31/335;A61K31/357;A61K31/34;A61K31/341;A61K31/38;A61K31/381;A61K31/40;A61K31/402;A61K31/47;A61K31/470;C07D215/02;C07D215/12;C07D215/14;C07D307/02;C07D307/04;C07D307/10;C07D307/12;C07D323/06;C07D405/02;C07D405/04;C07D407/02;C07D407/04;C07D409/02;C07D409/04 主分类号 A61K31/335
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