发明名称 |
PROCESS FOR PRODUCING SUBUNIT PEPTIDE ORIGINATING IN POLYMERPROTEIN |
摘要 |
A process for producing a subunit peptide originating in a polymer protein which has disulfide bonds in a subunit and between subunits. This process involves the following steps: (a) the step of denaturing the polymer protein or its subunit by using a protein denaturing agent in a solution, and then eliminating the denaturing agent from the solution in the presence of a polyoxyalkyl polyether having a functional group reacting with a thiol group , thereby unwinding the subunit; and (b) the step of separating the subunit, t o which the polyoxyalkyl polyether has been bonded, from the solution.
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申请公布号 |
CA2369869(A1) |
申请公布日期 |
2000.10.12 |
申请号 |
CA20002369869 |
申请日期 |
2000.03.31 |
申请人 |
AJINOMOTO CO., INC. |
发明人 |
YAMAMOTO, HIROSHI;FUKUCHI, NAOYUKI;KAYAHARA, TAKASHI;KITO, MORIKAZU;KAGEYAMA, SHUNSUKE |
分类号 |
C07K14/46;(IPC1-7):C07K1/14;C12N15/00 |
主分类号 |
C07K14/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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