METHOD AND COMPOSITIONS FOR PREVENTING OR REDUCING HIV INFECTION BY USE OF INHIBITORS FOR LEUCINE AMINOPEPTIDASE

摘要

In spite of having achieved an in depth and comprehensive genetic structure of the human immunodeficiency virus (HIV) and of that of its several structural and geographical clusters, a very limited success in the prevention and treatment of AIDS has been attained. Described herein is a method for preventing or reducing HIV infectivity by using an antibody specific for estrogen-stimulated leucine aminopeptidase (es-LAPase), or one or more inhibitors of LAPase activity, or a combination thereof. Also described is a method for preventing or reducing HIV infectivity by using an antibody specific for es-LAPase, one or more inhibitors of es-LAPase activity and an anti-estrogen compound. The novel compositions are also defined.