| 摘要 |
<p>The invention disclosed herein relates to liquid pharmaceutical compositions for oral administration which contain a drug or active ingredient dissolved in a liquid vehicle or carrier in which the liquid vehicle comprises a glyceride of a long chain fatty acid having from 14 to 22 carbon atoms and a lipophilic surfactant having an HLB of less than 10. Compositions of the invention provide increased drug or active ingredient stability and contain a liquid vehicle which is less reactive with the drug or active ingredient than free fatty acids. In one embodiment, the liquid pharmaceutical compositions contain testosterone undecanoate, a long chain triglyceride, and lauroglycol. The compositions can be orally administered and formulated in soft gel or hard shell capsule form.</p> |
