FORMULATION COMPRISING TESTOSTERON UNDECANOATE AND CASTOR OIL
摘要
Disclosed is a pharmaceutical formulation in the form of a capsule for oral administration comprising testosterone undecanoate as an active ingredient dissolved in a pharmaceutically acceptable liquid carrier, characterised in that the liquid carrier comprises at least 50 % by weight of castor oil. The choice of castor oil as the liquid carrier, in conjunction with the choice of testosterone undecanoate as the androgen, makes for a solution which can comprise about 200-250 mg/ml of TU. This is a novel achievement for any orally administerable solution of testosterone. The solution may also contain a lipophilic surfactant such as lauroglycol.
申请公布号
WO0059512(A1)
申请公布日期
2000.10.12
申请号
WO2000EP02677
申请日期
2000.03.27
申请人
AKZO NOBEL N.V.;NIJS DE, HENRIK;CHANDLER, SUSAN;PERRY, ELIZABETH, ANNE;FERDINANDO, JOSEPHINE, JOAN, CHRISTINE
发明人
NIJS DE, HENRIK;CHANDLER, SUSAN;PERRY, ELIZABETH, ANNE;FERDINANDO, JOSEPHINE, JOAN, CHRISTINE