发明名称 FORMULATION COMPRISING TESTOSTERON UNDECANOATE AND CASTOR OIL
摘要 Disclosed is a pharmaceutical formulation in the form of a capsule for oral administration comprising testosterone undecanoate as an active ingredient dissolved in a pharmaceutically acceptable liquid carrier, characterised in that the liquid carrier comprises at least 50 % by weight of castor oil. The choice of castor oil as the liquid carrier, in conjunction with the choice of testosterone undecanoate as the androgen, makes for a solution which can comprise about 200-250 mg/ml of TU. This is a novel achievement for any orally administerable solution of testosterone. The solution may also contain a lipophilic surfactant such as lauroglycol.
申请公布号 WO0059512(A1) 申请公布日期 2000.10.12
申请号 WO2000EP02677 申请日期 2000.03.27
申请人 AKZO NOBEL N.V.;NIJS DE, HENRIK;CHANDLER, SUSAN;PERRY, ELIZABETH, ANNE;FERDINANDO, JOSEPHINE, JOAN, CHRISTINE 发明人 NIJS DE, HENRIK;CHANDLER, SUSAN;PERRY, ELIZABETH, ANNE;FERDINANDO, JOSEPHINE, JOAN, CHRISTINE
分类号 A61K9/48;A61K31/568;A61K47/12;A61K47/44;A61P5/26;A61P15/16;A61P43/00 主分类号 A61K9/48
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