| 摘要 |
<p>Novel, orally active androgens are derivatives of 7α-methyl-19-nortestosterone. The compounds satisfy general formula (I) wherein R1 is O, (H, H), (H, OR), NOR, with R being hydrogen, (C1-6) alkyl, or (C1-6) acyl; R2 is selected from the group consisting of (C2-3) alkyl, isopropyl, (C2-3) 1-alkenyl, isopropenyl, 1,2-propadienyl, or (C2-3) 1-alkynyl, each optionally substituted by halogen; or R2 is cyclopropyl, or cyclopropenyl, each optionally substituted by (C1-2) alkyl, or halogen; R3 is hydrogen, (C1-2) alkyl, or ethenyl; R4 is (C1-2) alkyl; R5 is hydrogen, or (C1-15) acyl; and the dotted lines indicate optional bonds.</p> |
