发明名称 |
DSP-7 DUAL-SPECIFICITY MAP KINASE PHOSPHATASE |
摘要 |
Compositions and methods are provided for the treatment of conditions associated with cell proliferation, cell differentiation and/or cell survival. In particular, the dual-specificity phosphatase DSP-7, and polypeptide variants thereof that stimulate dephosphorylation of DSP-7 substrates, are provided. The polypeptides may be used, for example, to identify antibodies and other agents that inhibit DSP-7 activity. The polypeptides and agents may be used to modulate cell proliferation, cell differentiation and cell survival. |
申请公布号 |
WO0060098(A1) |
申请公布日期 |
2000.10.12 |
申请号 |
WO2000US09257 |
申请日期 |
2000.04.07 |
申请人 |
CEPTYR, INC.;LUCHE, RALF, M.;WEI, BO |
发明人 |
LUCHE, RALF, M.;WEI, BO |
分类号 |
G01N33/50;A61K45/00;A61P3/00;A61P21/00;A61P35/00;A61P37/00;A61P37/08;A61P43/00;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/16;C12N15/09;C12N15/55;C12P21/08;C12Q1/02;C12Q1/42;C12Q1/68;G01N33/15;G01N33/53;G01N33/566 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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