METHODS FOR IMPROVED LUMINESCENCE ASSAYS USING MICROPARTICLES

摘要

Disclosed and claimed are microparticles including an electroconductive material having one or more copies of an assay-ligand immobilized on the surface and a plurality of electrochemiluminescent moieties immobilized on the surface. Also provided are methods for conducting electrochemiluminescence measurements for binding an analyte of interest, which method includes the steps of (a) forming a complex between a microparticle and an assay-ligand immobilized on an electrode and (b) conducting an electrochemiluminescence measurement at the electrode in the presence of electrochemiluminescence reactants.