发明名称 |
Thermostable polymerase |
摘要 |
A thermostable enzyme having polymerase activity and substantially no nuclease activity is provided. The thermostable enzyme is characterized by comprising a sequence of nine amino acid residues at least proximal to the N-terminus that has less than 50% but greater than 40% amino acid sequence identity with residues 280 to 288 of the naturally occurring Thermus aquaticus polymerase. The subject enzyme finds use in a variety of different application in which polynucleotides are enzymatically produced, particularly in PCR based applications.
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申请公布号 |
US6130045(A) |
申请公布日期 |
2000.10.10 |
申请号 |
US19980096399 |
申请日期 |
1998.06.11 |
申请人 |
CLONTECH LABORATORIES, INC. |
发明人 |
WURST, HELMUT;QIU, ZHI-HAO |
分类号 |
C12N9/12;(IPC1-7):C12Q1/68 |
主分类号 |
C12N9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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