发明名称 |
Amphipathic oligonucleotides and polynucleotides having potent antiviral activity |
摘要 |
The present invention provides novel compositions that show potent antiviral activity against both DNA and RNA viruses. In particular, the present invention provides oligo- and polyribonucleotides with potent antiviral activity against HIV and HCMV. These compositions are thought to operate in a novel fashion at an early stage of viral infection, meeting the need for alternatives or synergistic therapies to the toxic treatments currently available. The present invention also discloses methods for synthesizing oligo- and polyribonucleotides showing antiviral activity.
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申请公布号 |
US6130324(A) |
申请公布日期 |
2000.10.10 |
申请号 |
US19990371909 |
申请日期 |
1999.08.10 |
申请人 |
UNIVERSITY OF UTAH RESEARCH FOUNDATION |
发明人 |
BROOM, ARTHUR D.;THORPE, ROBYN |
分类号 |
C07H21/00;(IPC1-7):C07H21/00 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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