METHOD OF PREPARING IMMUNOGLOBULINS FROM FRACTIONS FORMED IN HUMAN BLOOD PLASMA FRACTIONATION

摘要

immunology, preparative biochemistry. SUBSTANCE: method of preparing immunoglobulin preparations with high titer involves the following successive stages: fractionation of blood plasma from plasma pool where fraction that has polyclonal immunoglobulin G and can be used in industry is separated; preparing protein solution from protein components; affinity chromatography carrying out. Obtained immunoglobulins can be processed to the preparation that can be used for intravenous administration and stable in storage. Method provides preparing immunoglobulin preparation from human plasma fractions that are not utilized in conventional methods of plasma fractionation early. EFFECT: improved method of preparing. 22 cl, 14 tbl, 10 ex