| 摘要 |
PROBLEM TO BE SOLVED: To obtain a bone-strengthening agent useful for prophylactic or treating bone diseases such as osteoporosis by formulating an iron-lactoferrin as an active component. SOLUTION: This bone-strengthening agent contains an iron lactoferrin having at least 3 atoms of iron per every lactoferrin molecule as an active component. The iron lactoferrin is preferably an iron-lactoferrin conjugate and/or an iron- lactoferrin complex in which 10-700 mg of iron is combined with carbonate and/or bicarbonate in an amount of 15 mg or more per 1 g of the lactoferrin. Examples of the iron include ferrous sulfate and ferrous gluconate. The bone- strengthening agent may be compounded together with a component contributing bone-metabolism such as calcium, magnesium, vitamin D, vitamin K or an oligo sugar. The iron-lactoferrin is preferably formulated in such an amount that 1-10 mg of iron can be taken daily by an adult.
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