发明名称 |
TAXOID-BASE PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING |
摘要 |
chemical-pharmaceutical industry. SUBSTANCE: invention relates to stable and highly concentrated pharmaceutical composition. Composition has active substance taken among taxoid class, for example, docetaxel or its derivatives and one or some unsaturated phospholipids and nonsignificant amount of one or some negatively charged phospholipids additionally. Invention relates to also method of preparing indicated compositions. Invention eliminates shortcomings associated with the presence of excipients that exhibit toxicity in their high content. EFFECT: improved properties of composition. 28 cl, 25 ex
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申请公布号 |
RU2157200(C2) |
申请公布日期 |
2000.10.10 |
申请号 |
RU19960122523 |
申请日期 |
1995.04.24 |
申请人 |
RON-PULENK RORE S.A. |
发明人 |
MANFRED DURR;JORG-KRISTIAN KHAGER;ARMIN VENDEL' |
分类号 |
C07D305/14;A61K9/08;A61K31/335;A61K31/337;A61K31/34;A61K31/38;A61K31/42;A61K31/425;A61K47/24;A61K47/44;A61P35/00;(IPC1-7):A61K31/335 |
主分类号 |
C07D305/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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