发明名称 TETRAPEPTIDE SHOWING GEROPROTECTIVE ACTIVITY, PHARMACOLOGICAL AGENT BASED ON THEREOF AND METHOD OF ITS USE
摘要 medicine, geriatrics. SUBSTANCE: invention proposes biologically active compound tetrapeptide L-alanyl-L-glutamyl-L-asparagyl-glycine of the general formula: L-Ala-L-Glu-L-Asp-Gly and its using as agent showing geroprotective activity. Pharmacological agent containing effective amount of tetrapeptide or its salt as an active component is proposed for parenteral, intranasal, oral and topical using. Method of prophylaxis of early ageing involves prophylactic and/or curative administration in patient the pharmacological agent in doses 0.01-100 mcg/kg of body mass, at least once for period that is necessary to obtain the therapeutic effect. Invention can be used for prophylaxis of early body ageing. EFFECT: enhanced effectiveness of agent. 11 cl, 17 tbl, 10 ex
申请公布号 RU2157233(C1) 申请公布日期 2000.10.10
申请号 RU19990108841 申请日期 1999.05.11
申请人 A "INSTITUT BIOREGULJATSII I GERONTOLOGII" 发明人 KHAVINSON V.KH.
分类号 A61K38/00;A61K38/07;A61P11/06;A61P19/00;A61P39/06;A61P43/00;C07K5/10;C07K5/103 主分类号 A61K38/00
代理机构 代理人
主权项
地址