A rhoptry membrane antigen of the a sexual blood stages of Plasmodium falciparum, is characterised by: (i) being initially synthesized as a polypeptide having a relative molecular mass of approximately 80,000; (ii) being located in the neck region of the rhoptries of merozoites; and (iii) having the solubility characteristics and a hydrophobic domain typical of an integral membrane protein; or an antigenic fragment thereof.
申请公布号
CA1341115(C)
申请公布日期
2000.10.10
申请号
CA19890590737
申请日期
1989.02.10
申请人
SARAMANE PTY. LTD.
发明人
PYE, DAVID;SMYTHE, JASON ARTHUR;MARSHALL, VIKKI MAREE;SILVA, ANABEL;ANDERS, ROBIN FREDRIC;CREWTHER, PAULINE ELIZABETH;EDWARDS, STIRLING JOHN;CULVENOR, JANETTA GLADYS;KEMP, DAVID JAMES;PETERSON, MICHAEL GREGORY